Energy efficient partition-lightpath scheme for IP over WDM core networks

In this paper, the research focus on the development of energy saving schemes with roots in sleep modes that support the evolution of greener core optical IP networks. The cornerstone of the adopted strategy is partition-lightpath schemes underpinned by the hibernation state implemented through a modification of the intelligent control plane, in particular for transparent network architectures under different scenarios. An enhanced multi-level operational hibernation mode through partition-lightpath was defined including functionality, structure considering its implementation issues. Through the use of appropriate design parameters the impact on blocking probability, wavelengths assignment, LSP connection requests, degree of node connectivity and network utilization can be minimized while also achieving energy savings. Evaluation of this scheme indicates potential reduction in power consumption from 9% up to 17% at the expense of reduced network performance

Evaluation of video transmission of MAC protocols in wireless sensor network

Wireless Sensor Network (WSN) is a wireless network which consists of sensor nodes scattered in a particular area which are used to monitor physical or environment condition.Each node in WSN is also scattered in sensor field, so an appropriate scheme of MAC protocol should have to develop communication link for data transferring. Video transmission is one of the important applications for the future that can be transmitted with low aspect in side of cost and also power consumption. In this paper, comparison of five different MAC WSN protocol for video transmission namely IEEE 802.11 standard, IEEE 802.15.4 standard, CSMA/CA, Berkeley-MAC, and Lightweight-MAC protocol are studied.Simulation experiment has been conducted in OMNeT++ with INET network simulator software to evaluate the performance.Obtained results indicate that IEEE 802.11 works better than other protocol in term of packet delivery, throughput, and latency

Elucidating the Surface Functionality of Biomimetic RGD Peptides Immobilized on Nano-P(3HB-co-4HB) for H9c2 Myoblast Cell Proliferation

Biomaterial scaffolds play crucial role to promote cell proliferation and foster the regeneration of new tissues. The progress in material science has paved the way for the generation of ingenious biomaterials. However, these biomaterials require further optimization to be effectively used in existing clinical treatments. It is crucial to develop biomaterials which mimics structure that can be actively involved in delivering signals to cells for the formation of the regenerated tissue. In this research we nanoengineered a functional scaffold to support the proliferation of myoblast cells. Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] copolymer is chosen as scaffold material owing to its desirable mechanical and physical properties combined with good biocompatibility, thus eliciting appropriate host tissue responses. In this study P(3HB-co-4HB) copolymer was biosynthesized using Cupriavidus malaysiensis USMAA1020 transformant harboring additional PHA synthase gene, and the viability of a novel P(3HB-co-4HB) electrospun nanofiber scaffold, surface functionalized with RGD peptides, was explored. In order to immobilize RGD peptides molecules onto the P(3HB-co-4HB) nanofibers surface, an aminolysis reaction was performed. The nanoengineered scaffolds were characterized using SEM, organic elemental analysis (CHN analysis), FTIR, surface wettability and their in vitro degradation behavior was evaluated. The cell culture study using H9c2 myoblast cells was conducted to assess the in vitro cellular response of the engineered scaffold. Our results demonstrated that nano-P(3HB-co-4HB)-RGD scaffold possessed an average fiber diameter distribution between 200 and 300 nm, closely biomimicking, from a morphological point of view, the structural ECM components, thus acting as potential ECM analogs. This study indicates that the surface conjugation of biomimetic RGD peptide to the nano-P(3HB-co-4HB) fibers increased the surface wettability (15 ± 2°) and enhanced H9c2 myoblast cells attachment and proliferation. In summary, the study reveals that nano-P(3HB-co-4HB)-RGD scaffold can be considered a promising candidate to be further explored as cardiac construct for building cardiac construct

Throughput Analysis of WM-LEACH, LEACH, MH- LEACH and V-LEACH Protocol: a simulation based approach

This paper provides a passing description for some of routing protocols like LEACH, WM-LEACH, MH-LEACH and V-LEACH Protocol in Wireless Sensor Network (WSN) also a comparison study of these protocols based on one of performance matrices as throughput. Addition to this an attempt is done to calculate their throughput. The effect of these protocols are simulated through the MATLAB simulator. Finally, the throughput of the network increases with WM-LEACH with respect to send interval and number of bytes of data. In the WMLEACH, the throughput is higher than in other protocols which are compared in this research. This is because the WM-LEACH protocol reduces the communication cost between the domains by allowing more data in less time.-1

Analysis of signal propagation in an experiment room with epoxy covered floor for wireless sensor network applications

As sensor applications combined with wireless network becoming more of an everyday applications, the optimal deployment becomes ever increasing important as that would be a key important factor in the trade-off between cost and link quality. This paper reports on the effect of epoxy covered floor on signal propagation characteristics in an experiment room. Microchip developed motes were used to measure signal propagation in an experiment room where sensors would be deployed extensively. The results show that the signal strength for 30 cm antenna height provides a significant margin with respect to signal noise floor. As for the 5 cm antenna height, there is still around 25 dB margin in average before the signal reaches noise floor. Analysis shows that the log-distance model is the best fit to the measured data. Free Space Loss model seemed to under estimate the overall performance of the signals. An important conclusion from this study is that wireless mote deployment must consider the margin between the two signals of antenna heights and the margin to noise floor to avoid link quality deterioration especially for sensitive data acquisition applications

Differences in the Activity of Endogenous Bone Morphogenetic Protein Signaling Impact on the Ability of Induced Pluripotent Stem Cells to Differentiate to Corneal Epithelial-Like Cells

Cornea is a clear outermost layer of the eye which enables transmission of light onto the retina. The transparent corneal epithelium is regenerated by limbal stem cells (LSCs), whose loss/dysfunction results in LSCs deficiency (LSCD). Ex vivo expansion of autologous LSCs obtained from patient's healthy eye followed by transplantation onto the LSCs damaged/deficient eye, has provided a successful treatment for unilateral LSCD. However, this is not applicable to patient with total bilateral LSCD, where LSCs are lost/damaged from both eyes. We investigated the potential of human induced pluripotent stem cell (hiPSC) to differentiate into corneal epithelial-like cells as a source of autologous stem cell treatment for patients with total bilateral LSCD. Our study showed that combined addition of bone morphogenetic protein 4 (BMP4), all trans-retinoic acid and epidermal growth factor for the first 9 days of differentiation followed by cell-replating on collagen-IV-coated surfaces with a corneal-specific-epithelial cell media for an additional 11 days, resulted in step wise differentiation of human embryonic stem cells (hESC) to corneal epithelial progenitors and mature corneal epithelial-like cells. We observed differences in the ability of hiPSC lines to undergo differentiation to corneal epithelial-like cells which were dependent on the level of endogenous BMP signaling and could be restored via the activation of this signaling pathway by a specific transforming growth factor β inhibitor (SB431542). Together our data reveal a differential ability of hiPSC lines to generate corneal epithelial cells which is underlined by the activity of endogenous BMP signaling pathway